Tcl1 Expression in Chronic Lymphocytic Leukemia Is Regulated by miR-29 and miR-181
نویسندگان
چکیده
منابع مشابه
Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181.
B-cell chronic lymphocytic leukemia (B-CLL) is the most common human leukemia in the world. Deregulation of the TCL1 oncogene is a causal event in the pathogenesis of the aggressive form of this disease as was verified by using animal models. To study the mechanism of Tcl1 regulation in CLL, we carried out microRNA expression profiling of three types of CLL: indolent CLL, aggressive CLL, and ag...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2006
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-06-3613